I did 4 drain and fills on my 2006 the last few months because my transmission fluid was really dirty and I used the valvoline Maxlife Synthetic. Also added the Lube Gard Platinum. I called Lube Gard's customer support and was recommended by them to use the Lube Gard Platinum on the odyssey. It has made a very big difference in the transmission symptoms I was getting. I thought I was going to have to drop $3000 on a tranny rebuild.
Lube Gard recommends adding 1 oz per quart of fluid replaced. Don't dump a whole bottle in! I recommmend driving at least 100 miles in bettween drain and fills to get good circulation of fluid before your next drain and fill.