[JCsHonda]

We just helped someone fix their problem with CV's. Showed up as bad vibration on acceleration. A manual check of the CV's gave no indication of any play, looseness, or problems. Owner replaced CV on drivers side and problem is fixed. So, the give away that's it's a CV seems to be the vibration upon acceleration only.

http://www.odyclub.com/forums/52-2005-2010-odyssey/207153-05-ex-l-shaking-bad-all-rpms.html

 

[JCsHonda]

However, I have steering wheel shakes (in much less severity) at around 65-75MPH now.

I had that problem for years, yes years. I finally gave up trying to fix it and just figured it was a part of the vans character. I tried everything, new tires, wheel bearings, alignment checks, tires, balancing, component inspections, all of it.

At 150k mi I replaced struts/shocks (and one spring) with KYB's. Totally fixed the shaking problem. Steering wheel is even steadier now than when new. I mean absolutely still even up to 90+ mph. Kinda freaked me out for a few days. Still have not had an alignment or wheel balancing since the install and I'm running on the same set of halfway worn out Kumho tires.

Not saying that this is your answer, but certainly something to consider if you have higher miles and original components.

 

[JCsHonda]

I used a Cardone/Rock Auto CV in my Ody. I found it to be of very good quality and have not had any problems years later. What I'm saying is that maybe you should look at other things before shelling out the big bucks for new axles. Plus, you're not cheap, your smart! Vibration problems can be VERY difficult to solve, don't give up.