[jk43110]

Have a similar problem. Granted, a few years later...

 

[EarnhardtSports]

My 05 did this and I replaced the roller assembly and cured it. Bought rollers off ebay from Honda dealer $39 and about an hour job very easy to do.

 

[Autocrosser]

Rollers

http://www.odyclub.com/forums/52-2005-2010-odyssey/48283-2005-sliding-door-roller-replacement.html

 

[jraynal]

My door sometimes won't open or shut. But if I get it started using the handle (inside or outside, it will shut. The problem was the lock release actuator. ~$40 online. Common issue. Also, look at the rollers on the door track. Ensure that you see to good nylon rollers. If they are both there, chances are that it's good and you don't have to replace it. It took me ~30 min to remove the door plastic trim pieces (two). The hardest part was getting the interior handle off (2 min).